This web-based application provides an interactive platform to explore all analysis results generated as part of the OHDSI LEGEND study.

These results are featured in:

Suchard MA, Schuemie MJ, Krumholz H, You SC, Chen RJ, Pratt N, Reich CG, Duke J, Madigan D, Hripcsak G, Ryan PB
Comprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a systematic, multinational, large-scale analysis.
Lancet, 2019

### External links

**Figure 2.**
Preference score distribution. The preference score is a transformation of the propensity score
that adjusts for differences in the sizes of the two treatment groups. A higher overlap indicates subjects in the
two groups were more similar in terms of their predicted probability of receiving one treatment over the other.

**Figure 4.**
Systematic error. Effect size estimates for the negative controls (true hazard ratio = 1)
and positive controls (true hazard ratio > 1), before and after calibration. Estimates below the diagonal dashed
lines are statistically significant (alpha = 0.05) different from the true effect size. A well-calibrated
estimator should have the true effect size within the 95 percent confidence interval 95 percent of times.

**Figure 8.**
Fitted null distributions per data source.